Competing pursuits
NHS: consulting charges: Agenus, Puretech, Regeneron, Novartis, Numab, AstraZeneca, GSK, ABL Bio, Revitope, Roche/Genentech, Boehringer Ingelheim. Grants or funds: Roche/Genentech, Pfizer, Merck, BMS, AstraZeneca, Puretech, Immunocore, Regeneron, Agenus. JTi: advisory council or committee: Amgen, Novartis, AstraZeneca, Merck Serono, Merck Sharp & Dohme, Pierre Fabre, Bristol–Myers Squibb, Daiichi–Sankyo, Gilead, Limbic Digital Media, Illumina, Beigene, Roche. Honoraria: Amgen, Novartis, AstraZeneca, Merck Serono, Merck Sharp & Dohme, Pierre Fabre, Bristol–Myers Squibb, Daiichi–Sankyo, Gilead, Limbic Digital Media, Illumina, Beigene, Roche. Consulting price: Haystack Oncology. SK: possession of inventory/shares: Lutris, Iylon, Frontier Medicines, Xilis, Navire. Consulting price: Genentech, EMD Serono, Merck, Holy Stone Healthcare, Novartis, Lilly, Boehringer Ingelheim, AstraZeneca/MedImmune, Bayer Well being, Redx Pharma, Ipsen, HalioDx, Lutris, Jacobio, Pfizer, Repare Therapeutics, Inivata, GSK, Jazz Prescribed drugs, Iylon, Xilis, AbbVie, Amal Therapeutics, Gilead Sciences, Mirati Therapeutics, Flame Biosciences, Servier, Carina Biotech, Bicara Therapeutics, Endeavor BioMedicines, Numab, Johnson & Johnson/Janssen, Genomic Well being, Frontier Medicines, Replimune, Taiho Pharmaceutical, Cardiff Oncology, Ono Pharmaceutical, Bristol–Myers Squibb-Medarex, Amgen, Tempus, Basis Drugs, Harbinger Oncology, Inc, Takeda, CureTeq, Zentalis, Black Stone Therapeutics, NeoGenomics Laboratories, Accademia Nazionale Di Medicina, Tachyon Therapeutics. Grants or funds: Sanofi, Biocartis, Guardant Well being, Array BioPharma, Genentech/Roche, EMD Serono, MedImmune, Novartis, Amgen, Lilly, Daiichi–Sankyo. MD: employment: Sandoz (partner). Advisory council or committee: AbbVie, Rafael, AstraZeneca, Takeda, Daiichi–Sankyo, Roche, Bayer. Honoraria: Pierre Fabre, Servier, MSD, Daiichi–Sankyo, Bayer. Consulting charges: Boehringer, MSD, Beigene. Grants or funds: Keocyt, Roche, Bayer. EC: grants or funds: Medical trials sponsored by AstraZeneca. RD: honoraria: Roche, Ipsen, Amgen, Servier, Sanofi, Libbs, Merck Sharp & Dohme, Lilly, AstraZeneca, Janssen, Takeda, Bristol–Myers Squibb, GSK, Gilead. Consulting charges: Roche, Basis Drugs. Grants or funds: Novartis, Daiichi–Sankyo, GSK, AstraZeneca. Investor in Trialing Well being, S.L. AH: consulting charges: Amgen, Basilea, Bristol–Myers Squibb, Incyte, Relay Therapeutics, Sanofi, Servier, Tahio. Fee or honoraria for lectures, displays, audio system bureaus, manuscript writing, or academic occasions: Incyte, Seagen, Servier. Participation on a Knowledge Security Monitoring Board or Advisory Board: Basilea, QED Therapeutics, Relay Therapeutics, Tahio. MJR: consulting charges: Seattle Genetics, Bristol–Myers Squibb. EE: honoraria (private): Amgen, Bayer, Hoffman La-Roche, Merck Serono, MSD, Novartis, Organon, Pfizer, Pierre Fabre, Sanofi, Seagen, Servier, Takeda. Consulting charges (private): Amgen, Bayer, Hoffman La-Roche, Merck Serono, MSD, Novartis, Organon, Pfizer, Pierre Fabre, Sanofi, Seagen, Servier, Takeda. JCo: employment by, and inventory/share possession in AstraZeneca. Honoraria: AstraZeneca. JCa: employment by, and inventory/share possession in AstraZeneca. YS-H: employment by, and inventory/share possession in AstraZeneca. NH: employment by, and inventory/share possession in AstraZeneca. ZAC: employment by, and inventory/share possession in AstraZeneca. RK: employment by, and inventory/share possession in AstraZeneca. Patent associated to anti-CD73 antibody. JTa: inventory/share possession in Oniria Therapeutics. Honoraria: Instructional collaboration with Imedex/HMP, Medscape Schooling, MJH Life Sciences, PeerView Institute for Medical Schooling and Physicians Schooling Useful resource (PER). Consulting charges: for Array Biopharma, AstraZeneca, Bayer, Boehringer Ingelheim, Cardiff Oncology, Chugai, Daiichi–Sankyo, F. Hoffmann-La Roche Ltd, Genentech Inc, HalioDX SAS, Hutchison MediPharma Worldwide, Ikena Oncology, Inspirna Inc, IQVIA, Lilly, Menarini, Merck Serono, Merus, MSD, Mirati, Neophore, Novartis, Ona Therapeutics, Orion Biotechnology, Peptomyc, Pfizer, Pierre Fabre, Samsung Bioepis, Sanofi, Scandion Oncology, Scorpion Therapeutics, Seattle Genetics, Servier, Sotio Biotech, Taiho, Tessa Therapeutics, TheraMyc, Tolremo Therapeutics.
Ethics approval and consent to take part
All sufferers offered written knowledgeable consent. The research was carried out in accordance with the Declaration of Helsinki and the Worldwide Convention on Harmonisation Good Medical Observe pointers. The protocol and all modifications have been authorized by related ethics committees and regulatory authorities at every web site. These websites embody: Peter MacCallum Most cancers Heart Human Analysis Ethics Committee, Melbourne, VIC, Australia; Bellberry Human Analysis Ethics Committee, Eastwood, SA, Australia; College Well being Community Analysis Ethics Board, Toronto, ON, Canada; Lakeridge Well being Analysis Ethics Board—Lakeridge Well being, Oshawa, ON, Canada; Well being Analysis Ethics Board of Alberta—Most cancers Committee, Edmonton, AB, Canada; Saint Mary’s Hospital Analysis Ethics Committee, Montreal, QC, Canada; Le Comité de safety des personnes Sud-Est VI—C.H.U.—Administration Centrale, Clermont-Ferrand, France; Comite de Etica de Investigacion con Medicamentos – Hospital Universitario 12 de Octubre, Madrid, Spain; Western Institutional Overview Board, Puyallup, WA, USA; Memorial Sloan Kettering Most cancers Heart Institutional Overview Board, New York, NY, USA; College of California, Los Angeles—Workplace of the Human Analysis Safety Program, Los Angeles, CA, USA; Rhode Island Hospital Institutional Overview Board, Windfall, RI, USA; The College of Texas MD Anderson Most cancers Heart Institutional Overview Board, Houston, TX, USA; College of Michigan Medical College Institutional Overview Board, Ann Arbor, MI, USA.
Consent for publication
Not relevant.